Hi Akshay, How are you? We need to double check on the data sheet from you. When you read the AFE5801 data sheet's almost very last page with "REVISION HISTORY". It mentions: "Deleted INVERT_CHANNEL and MSB_FIRST rows from register map table" "Deleted INVERT_CHANNEL register description" "Deleted MSB_FIRSTL register description" So please make sure and double check on your register settings. Please don't use "invert channel" mode and please don't use "MSB First" mode (Only "LSB First" mode can be used). And then you should be able to re-run AFE5801 device with higher speed 40MSPS. Hope this can solve your problem. Thank you! Best regards, Chen
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